ABSTRACT
Objective:To investigate the clinical significance of peripheral blood neutrophil to lymphocyte ratio in patients with 2 type diabetes mellitus complicated acute cerebral infarction, so as to provide theoretical basis for clinical diagnosis and treatment. Methods:From Jan. 2014 to Dec. 2016 year,136 patients with 2 type diabetes mellitus complicated acute cerebral infarction were selected as research group and 68 diabetic patients undergoing physical examination were selected as the control group. White blood cell count(WBC),neutrophil count(NC),lymphocyte count(LC) and neutrophil to lymphocyte ratio(NLR) were detected and calculated. The role of WBC,NC,LC and NLR in the diagnosis of type 2 diabetes mellitus combined with acute cerebral infarction were evaluated by receiver operating characteristic curve(ROC) and area under the curve(AUC). Results:The levels of WBC,NC and NLR in research group were significantly higher than those of in control group(P＜0. 05),while the level of LC was significantly lower than that of in control group(P＜0. 05). The levels of WBC,NC and NLR in research group increased with the increase of NIHSS score(P＜0. 05),and the level of LC decreased with the increase of NIHSS score(P＜0. 05). The area under the curve of NLR,WBC,NC and LC in diagnosing diabetes combined with acute cerebral infarction were respectively 0. 856,0. 717,0. 685 and 0. 321. The sensitivity were respectively 0. 838,0. 596,0. 517 and 0. 208. The specificity are respectively 0. 868,0. 838,0. 793 and 0. 559. Conclusion:NLR could be used as a marker for the diagnosis of type 2 diabetes with acute cerebral infarction.
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect and influential factors of strong stimulation of acupoints around eyes by reducing method of twisting the needle for treatment of adolescent myopia, and to compare the different curative effects of both weak and strong stimulus intensities and wearing glasses in daytime.</p><p><b>METHODS</b>According to the principle of knowing and permission, the patients were divided into a strong stimulation group (60 cases, 120 eyes), a weak stimulation group (60 cases, 120 eyes) and a wearing glasses group (60 cases, 120 eyes). Both the strong stimulation group and the weak stimulation group were treated by reducing method of twisting the needle, with Cuanzhu (BL 2), Yuyao (EX-HN 4), Sizhukong (TE 23), Sibai (ST 2) and Taiyang (EX-HN 5) selected. Each acupoint was twisted 360 and 90 times per min for the strong stimulation group, and 90 degrees and 60 times per min for the weak stimulation group; the wearing glasses group were not treated with acupuncture, but with wearing glasses in daytime.</p><p><b>RESULTS</b>After treatment with the reducing method of twisting the needle, the vision improved (P < 0.01), with more obviously increased in the strong stimulation group than the weak stimulation group (P < 0.01), and there was no significant change of vision in the wearing glasses group. The age and the myopic degree of the patient before treatment were closely related with the change of vision after treatment (P < 0.01).</p><p><b>CONCLUSION</b>The reducing method of twisting the needle has a definite clinical therapeutic effect on adolescent myopia; strong stimulation has a better effect than the weak one; the age and the myopic degree of the patient possibly influence the therapeutic effect.</p>